the role of jingxin grinding portable hair grinder in forensic mass spectrometry detection.
ministry of justice:
take sf/z jd0107022-2018 as example:
targets: δ9-tetrahydrocannabinol, cannabidiol, cannabidiol
internal standard: methoxyphenamine/or similar
operating procedures:
ministry of justice: liquid chromatography-tandem mass spectrometry detection methods for 16 tryptamine-type new psychoactive substances and their metabolites in hair sf/t 0065-2020
internal standard 1mg/ml psilocybin d4/psiloxin d10/or similar
target:
tryptamines:
5-methoxy-n,n-diisopropyltryptamine (5-me0-dipt)
5-methoxy-n-methyl-n-isopropyltryptamine (5-me0-mipt)
5-methoxy-n,n-diallyltryptamine (5-me0-dalt)
5-methoxy-n,n-dimethyltryptamine (5-me0-dmt)
5-hydroxy-n,n-diisopropyltryptamine (5-0h-dipt)
4-hydroxy-n,n-diisopropyltryptamine (4-0h-dipt)
n,n-dimethyltryptamine (dmt)
n,n-dipropyltryptamine (dpt)
5-methoxy-n-isopropyltryptamine (5-me0-nipt)
4-hydroxy-n-methyl-n-ethyltryptamine (4-0h-met)
psilocin）
psilocybin）
4-hydroxy-n-methyl-n-isopropyltryptamine (4-0h-mipt)
4-acetoxy-n,n-diisopropyltryptamine (4-acetoxy-dipt)
5-methoxy-2-methyltryptamine (5-me0-amt)
n-isopropyltryptamine (nipt)
in the specification sf/z jd0107022-2018, it is recommended to adopt the method of first grinding and then weighing for sampling, while in sf/t 0065-2020, the method of accurate weighing and then grinding is adopted. which is more applicable?
2 options are available!
1. in the specification, the hair is washed, dried, cut into pieces, and weighed after grinding.
advantages: 1mm hair section is prone to static electricity. after cutting it, it will make the hair stick to the inner wall of the test tube and it is not easy to transfer and weigh. therefore, it is relatively easy to use dry freeze grinding before weighing.
disadvantages: after dry freeze grinding, the debris that is easily mixed into the grinding balls causes inaccurate weights, and the concentration of the test results is low. in order to avoid this phenomenon, it is necessary to use metal grinding balls, but the cost is more expensive and one-time use will increase the cost.
2. in the standard, the hair is washed, dried, cut into pieces, weighed, and ground after adding the internal standard solution.
advantages: the precise weight of the hair after grinding does not change, and the data conclusions are more accurate.
disadvantages: hair is prone to static electricity. after being cut and weighed, the hair will stick to the inner wall of the test tube and it is not easy to transfer and weigh. to solve this problem, it is necessary to accurately record the quality information of the 1mm hair section for calculation, and use the precision better balance weighing.
in addition, for sample pretreatment, except for hair washing and grinding, which requires manual operations, atlas-lext series products can be used to automate sample pretreatment in the whole process: compared with manual sample analysis, the automated solution is simpler and faster.
the hair grinder used in the grinding process of the product is exactly the portable hair grinder produced by jingxin. the product jxmf-06 portable hair grinder drives them to strike the inner surface of the arc with high energy by the inertia of the grinding balls/beads. the sample material, so as to achieve the effect of crushing and grinding. the movement of the adapter can be superimposed with the movement of the inner ball to thoroughly mix the sample.
main feature：
1. portable design, small size and light weight, easy to carry.
2. high throughput, good effect, fast and accurate.
3. powerful stirring for cracking, grinding or homogenization.
4. simple operation and safe design to ensure safe operation.
5. portable mobile power adapter, can be used anytime, anywhere.
advantages：
easy to operate: easy-to-operate fixture design, just twist it lightly
strong applicability: can be equipped with a power bank, available anytime, anywhere
small size: only 210*140*150 mm, slightly larger than the handheld centrifuge
high cost performance: the price is only a few thousand yuan
high efficiency: 1-6 samples, only 1 minute for dry grinding and 3 minutes for wet grinding
no contamination: each sample is processed in a separate grinding tube to avoid cross-contamination
shanghai jingxin industrial development co., ltd. is a high-tech enterprise specializing in the research and development, production, sales and service of life science instruments and reagents.
the predecessor of jingxin industrial development co., ltd. was the branch office of german fengyue industrial company in shanghai (the former shanghai jingxin experimental science and technology research department). at the same time, it also pays attention to technological innovation, and constantly develops experimental instruments favored by customers.
the company relies on a dynamic and imaginative team to continuously innovate and improve products. at the same time, the products are produced in strict accordance with the iso9001 standard, integrated design, exquisite materials, fine processing, strict inspection of each instrument, and focus on the "jingxin" brand. advanced hardware and software also provide a more solid foundation for the production of high-quality products.
relying on stable product quality, high-quality after-sales service, and rigorous work style, our company's first "tissuelyser series grinder" and "semiconductor refrigeration technology-based" products have been successively sold in chinese academy of sciences, academy of agricultural sciences, academy of medical sciences and other advanced research institutes. therefore, the national key laboratories of shanghai jiaotong university, fudan university, zhejiang university, chinese university of hong kong, hong kong polytechnic university and other colleges and universities are favored and widely used.
with the progress of scientific research and the change of technological revolution, many new demands will be born, in order to be more conducive to experiments, more convenient to do research, or to improve the existing product technology so as to be more suitable for people to use. the direction we are committed to is to find out these potential needs, to create new products, or to concretize, industrialize and market some conceptual products. jingxin technology will work hard to create a new business opportunity and industry with its partners.
